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Potential pitfalls in MitoChip detected tumor-specific somatic mutations: a call for caution when interpreting patient data

BACKGROUND: Several investigators have employed high throughput mitochondrial sequencing array (MitoChip) in clinical studies to search mtDNA for markers linked to cancers. In consequence, a host of somatic mtDNA mutations have been identified as linked to different types of cancers. However, closer...

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Detalhes bibliográficos
Main Authors: Palanichamy, Malliya Gounder, Zhang, Ya-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988032/
https://ncbi.nlm.nih.gov/pubmed/21034508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-597
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