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Heterologous transmembrane signaling by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells.

A hybrid receptor molecule composed of the extracellular ligand-binding domain of the human insulin receptor and the transmembrane and cytoplasmic (protein-tyrosine kinase) domains of the chicken sarcoma virus UR2 transforming protein p68gag-ros has been constructed and expressed in Chinese hamster...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ellis, L, Morgan, D O, Jong, S M, Wang, L H, Roth, R A, Rutter, W J
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298801/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3299376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.15.5101
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