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A defect in Δ(6 )and Δ(5 )desaturases may be a factor in the initiation and progression of insulin resistance, the metabolic syndrome and ischemic heart disease in South Asians
The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ(6 )and Δ(5 )desaturases and consequent low plasma and tissue concentrations of polyunsaturated fatty acids such as γ-linolenic acid (GLA), dihomo-γ-li...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987992/ https://ncbi.nlm.nih.gov/pubmed/21062475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-130 |
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