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Thermodynamic modeling of transcription: sensitivity analysis differentiates biological mechanism from mathematical model-induced effects

BACKGROUND: Quantitative models of gene expression generate parameter values that can shed light on biological features such as transcription factor activity, cooperativity, and local effects of repressors. An important element in such investigations is sensitivity analysis, which determines how str...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dresch, Jacqueline M, Liu, Xiaozhou, Arnosti, David N, Ay, Ahmet
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987881/
https://ncbi.nlm.nih.gov/pubmed/20969803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-142
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