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Effects of gene therapy on muscle 18S rRNA expression in mouse model of ALS

BACKGROUND: The efficiency of gene therapy experiments is frequently evaluated by measuring the impact of the treatment on the expression of genes of interest by quantitative real time PCR (qRT-PCR) and by normalizing these values to those of housekeeping (HK) genes constitutively expressed througho...

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Main Authors: Moreno-Igoa, María, Manzano, Raquel, Oliván, Sara, Calvo, Ana C, Toivonen, Janne M, Osta, Rosario
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987871/
https://ncbi.nlm.nih.gov/pubmed/21044297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-275
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