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Creation of a novel peptide with enhanced nuclear localization in prostate and pancreatic cancer cell lines
BACKGROUND: For improved uptake of oligonucleotide-based therapy, the oligonucleotides often are coupled to peptides that facilitate entry into cells. To this end, novel cell-penetrating peptides (CPPs) were designed for mediating intracellular uptake of oligonucleotide-based therapeutics. The novel...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987774/ https://ncbi.nlm.nih.gov/pubmed/21029412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-79 |
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