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Transcriptome bioinformatic analysis identifies potential therapeutic mechanism of pentylenetetrazole in down syndrome

BACKGROUND: Pentylenetetrazole (PTZ) has recently been found to ameliorate cognitive impairment in rodent models of Down syndrome (DS). The mechanism underlying PTZ's therapeutic effect in DS is however not clear. Microarray profiling has previously reported differential expression, both up- an...

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Bibliographic Details
Main Author: Sharma, Abhay
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987760/
https://ncbi.nlm.nih.gov/pubmed/21029440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-3-7
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