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A novel synthesis of 3-(substituted)pyrimido[4,5-c]pyridazine-5,7(1H,6H)-diones

An improved synthesis of 3-(substituted)pyrimido[4,5-c]pyridazine-5,7(1H,6H)-diones, a known subclass of 4-deazatoxoflavins, is reported. The approach involves treatment of 3-methyl-6-(1-methylhydrazinyl) uracil with representative phenyl and alkyl glyoxal monohydrates, which in turn are obtained by...

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Main Authors: Turbiak, Anjanette J., Kampf, Jeff W., Hollis Showalter, H. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987637/
https://ncbi.nlm.nih.gov/pubmed/21103016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.01.007
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