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Canonical Wnt signaling modulates Tbx1, Eya1 and Six1 expression, restricting neurogenesis in the otic vesicle
To understand the mechanism by which canonical Wnt signaling sets boundaries for pattern formation in the otic vesicle (OV), we examined Tbx1 and Eya1-Six1 downstream of activated β-catenin. Tbx1, the gene for velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS), is essential for inner ear devel...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987613/ https://ncbi.nlm.nih.gov/pubmed/20503367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22308 |
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