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Growth hormone-releasing hormone (GHRH) antagonists inhibit the proliferation of androgen-dependent and -independent prostate cancers

The antiproliferative effects of an antagonist of growth hormone-releasing hormone (GHRH) JV-1-38 were evaluated in nude mice bearing s.c. xenografts of LNCaP and MDA-PCa-2b human androgen-sensitive and DU-145 androgen-independent prostate cancers. In the androgen-sensitive models, JV-1-38 greatly p...

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Detalhes bibliográficos
Main Authors: Letsch, Markus, Schally, Andrew V., Busto, Rebeca, Bajo, Ana M., Varga, Jozsef L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298759/
https://ncbi.nlm.nih.gov/pubmed/12538852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337496100
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