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HLA-G gene repression is reversed by demethylation

The HLA-G molecule plays an important role in immune tolerance, protecting the fetus from maternal immune attack, and probably contributes to graft tolerance and tumor escape from the host immune system. HLA-G expression is tightly regulated and involves mechanisms acting in part at the transcriptio...

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Bibliografiske detaljer
Main Authors: Moreau, Philippe, Mouillot, Gaël, Rousseau, Philippe, Marcou, Céline, Dausset, Jean, Carosella, Edgardo D.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC298749/
https://ncbi.nlm.nih.gov/pubmed/12552087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0337539100
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