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REGγ modulates p53 activity by regulating its cellular localization

The proteasome activator REGγ mediates a shortcut for the destruction of intact mammalian proteins. The biological roles of REGγ and the underlying mechanisms are not fully understood. Here we provide evidence that REGγ regulates cellular distribution of p53 by facilitating its multiple monoubiquity...

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Detalhes bibliográficos
Main Authors: Liu, Jian, Yu, Guowu, Zhao, Yanyan, Zhao, Dengpan, Wang, Ying, Wang, Lu, Liu, Jiang, Li, Lei, Zeng, Yu, Dang, Yongyan, Wang, Chuangui, Gao, Guang, Long, Weiwen, Lonard, David M., Qiao, Shanlou, Tsai, Ming-Jer, Zhang, Bianhong, Luo, Honglin, Li, Xiaotao
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987440/
https://ncbi.nlm.nih.gov/pubmed/21084564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.067405
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