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Two novel missense mutations in HAIRY-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis

Spondylocostal dysostosis (SCD) is an inherited disorder with abnormal vertebral segmentation that results in extensive hemivertebrae, truncal shortening and abnormally aligned ribs. It arises during embryonic development by a disruption of formation of somites (the precursor tissue of the vertebrae...

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Detalhes bibliográficos
Main Authors: Sparrow, Duncan B, Sillence, David, Wouters, Merridee A, Turnpenny, Peter D, Dunwoodie, Sally L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987349/
https://ncbi.nlm.nih.gov/pubmed/20087400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.241
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