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Modulation of aberrant NF1 pre-mRNA splicing by kinetin treatment

Neurofibromatosis type 1 is one of the most common neurocutaneous autosomal dominant disorders. It is caused by mutations in the neurofibromatosis type 1 (NF1) gene and approximately 30–40% of them affect the correct splicing of NF1 pre-mRNA. In this report, we evaluate the effect of five different...

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Detalhes bibliográficos
Main Authors: Pros, Eva, Fernández-Rodríguez, Juana, Benito, Llúcia, Ravella, Anna, Capellá, Gabriel, Blanco, Ignacio, Serra, Eduard, Lázaro, Conxi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987307/
https://ncbi.nlm.nih.gov/pubmed/19935827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.212
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