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N-Heterocyclic Carbene-Initiated α-Acylvinyl Anion Reactivity: Additions of α-Hydroxypropargylsilanes to Aldehydes

[Image: see text] Highly substituted α,β-unsaturated ketones are prepared by the N-heterocyclic carbene-initiated addition of α-hydroxypropargylsilanes to aldehydes. This strategy serves as a highly efficient alternative to the standard Morita–Baylis–Hillman (MBH) approaches for these types of compo...

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Detalhes bibliográficos
Main Authors: Reynolds, Troy E., Stern, Charlotte A., Scheidt, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987273/
https://ncbi.nlm.nih.gov/pubmed/17539656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0710515
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