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Design and evaluation of a panel of single-nucleotide polymorphisms in microRNA genomic regions for association studies in human disease

MicroRNAs (miRNA) are recognized posttranscriptional gene repressors involved in the control of almost every biological process. Allelic variants in these regions may be an important source of phenotypic diversity and contribute to disease susceptibility. We analyzed the genomic organization of 325...

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Bibliografiske detaljer
Main Authors: Muiños-Gimeno, Margarita, Montfort, Magda, Bayés, Mònica, Estivill, Xavier, Espinosa-Parrilla, Yolanda
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987200/
https://ncbi.nlm.nih.gov/pubmed/19809479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.165
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