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A genome scan in affected sib-pairs with familial vesicoureteral reflux identifies a locus on chromosome 5

The basis for vesicoureteral reflux (VUR) is considered to be primarily genetic, with a 30–50% incidence of VUR in first-degree relatives of patients. The search for the causative gene or genes has been elusive, likely because of VUR being genetically heterogeneous with complex inheritance patterns....

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Detalhes bibliográficos
Main Authors: Briggs, Christine E, Guo, Chao-Yu, Schoettler, Cynthia, Rosoklija, Ilina, Silva, Andres, Bauer, Stuart B, Retik, Alan B, Kunkel, Louis, Nguyen, Hiep T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987194/
https://ncbi.nlm.nih.gov/pubmed/19690587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.142
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