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Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men
DNA methylation marks, a key modification of imprinting, are erased in primordial germ cells and sex specifically re-established during gametogenesis. Abnormal epigenetic programming has been proposed as a possible mechanism compromising male fertility. We analysed by pyrosequencing the DNA methylat...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2987171/ https://ncbi.nlm.nih.gov/pubmed/19584898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.117 |
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