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Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts

Cells progressing through the cell cycle must commit irreversibly to mitosis without slipping back to interphase before properly segregating their chromosomes. A mathematical model of cell-cycle progression in cell-free egg extracts from frog predicts that irreversible transitions into and out of mi...

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Detalles Bibliográficos
Main Authors: Sha, Wei, Moore, Jonathan, Chen, Katherine, Lassaletta, Antonio D., Yi, Chung-Seon, Tyson, John J., Sible, Jill C.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC298711/
https://ncbi.nlm.nih.gov/pubmed/12509509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0235349100
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