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Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma

Activating oncogenic mutations of receptor tyrosine kinases (RTKs) have been reported in several types of cancers. In many cases, genomic rearrangements lead to the fusion of unrelated genes to the DNA coding for the kinase domain of RTKs. All RTK-derived fusion proteins reported so far display olig...

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Detalhes bibliográficos
Main Authors: Charest, Alan, Kheifets, Vicky, Park, Julie, Lane, Keara, McMahon, Kevin, Nutt, Cathy L., Housman, David
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC298701/
https://ncbi.nlm.nih.gov/pubmed/12538861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242741799
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