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Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain.

Dopamine receptor types D1 and D2 can oppose or enhance each other's actions for electrical, biochemical, and psychomotor effects. We report a D1-D2 interaction in homogenized tissue as revealed by ligand binding. D2 agonists lowered the binding of [3H]raclopride to D2 receptors in striatal and ante...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Seeman, P, Niznik, H B, Guan, H C, Booth, G, Ulpian, C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2574862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10156
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