Novel promoter and exon mutations of the BMPR2 gene in Chinese patients with pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH), which is clinically characterized by a sustained elevation in mean pulmonary artery pressure leading to significant morbidity and mortality, is caused by intense remodeling of small pulmonary arteries by endothelial and smooth muscle proliferation. Genetic stud...

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Detalhes bibliográficos
Principais autores: Wang, Hu, Li, Wen, Zhang, Weili, Sun, Kai, Song, Xiaodong, Gao, Shuo, Zhang, Channa, Hui, Rutai, Hu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986562/
https://ncbi.nlm.nih.gov/pubmed/19223935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.3
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