Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.

We report that tumor necrosis factor alpha (TNF-alpha) mRNA is increased after treatment with x-rays in certain human sarcoma cells. An increase in TNF-alpha mRNA is accompanied by the increased production of TNF-alpha protein. TNF-alpha enhances radiation lethality in both TNF-alpha-producing and -...

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Bibliographic Details
Main Authors: Hallahan, D E, Spriggs, D R, Beckett, M A, Kufe, D W, Weichselbaum, R R
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC298653/
https://ncbi.nlm.nih.gov/pubmed/2602359
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