Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity.
To design and direct at will the specificity of T cells in a non-major histocompatibility complex (MHC)-restricted manner, we have generated and expressed chimeric T-cell receptor (TcR) genes composed of the TcR constant (C) domains fused to the antibody's variable (V) domains. Genomic expression ve...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1989
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10024 |
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