Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways.

Nuclear protein IRF-1 (interferon regulatory factor 1) was earlier shown to bind to cis-acting regulatory elements present on interferon (IFN)-alpha/beta genes and some IFN-inducible genes. Here we show that in both human FS-4 and murine L929 cells, steady-state levels of IRF-1 mRNA were increased b...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fujita, T, Reis, L F, Watanabe, N, Kimura, Y, Taniguchi, T, Vilcek, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298617/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2557635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9936
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