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Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs.

To show conclusively that the critical structural deformation of double-helical DNA that is induced by the binding of quinoxaline antibiotics does not involve the formation of Hoogsteen base pairs, we have prepared a DNA fragment containing the nucleoside analog 7-deaza-2'-deoxyadenosine in one of t...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: McLean, M J, Seela, F, Waring, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298566/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2602369/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.9687
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