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Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1.

Human immunodeficiency virus type 1 (HIV-1) contains an open reading frame called nef at the 3' end of its genome. The nef gene product has been reported to down-regulate viral growth by suppressing viral transcription through interaction with the long terminal repeat region. We have compared two is...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kim, S, Ikeuchi, K, Byrn, R, Groopman, J, Baltimore, D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2687883/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9544
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