Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.

The definition of human immunodeficiency virus type 1 (HIV-1) immunogenic epitopes is central to the rational design of AIDS vaccine strategies. In this study, we have generated seven HIV-1 reverse transcriptase-specific cytotoxic T-lymphocyte (CTL) clones from the peripheral blood of two seropositi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Walker, B D, Flexner, C, Birch-Limberger, K, Fisher, L, Paradis, T J, Aldovini, A, Young, R, Moss, B, Schooley, R T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480604/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9514
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