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Blocking of passive sensitization of human mast cells and basophil granulocytes with IgE antibodies by a recombinant human epsilon-chain fragment of 76 amino acids.

The recombinant peptide corresponding to residues 301-376 at the junction of constant regions 2 and 3 of the human IgE epsilon chain blocked the in vivo passive sensitization of human skin mast cells and in vitro sensitization of human basophil granulocytes with human IgE antibodies. An injection of...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Helm, B, Kebo, D, Vercelli, D, Glovsky, M M, Gould, H, Ishizaka, K, Geha, R, Ishizaka, T
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2512581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9465
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