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Urate oxidase: primary structure and evolutionary implications.

Urate oxidase, or uricase (EC 1.7.3.3), is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals. In humans and certain other primates, however, the enzyme has been lost by some unknown mechanism. To identify the molecular basis for this loss, urate oxidase cDNA...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Wu, X W, Lee, C C, Muzny, D M, Caskey, C T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1989
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298506/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2594778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9412
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