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100-kDa polypeptides in peripheral clathrin-coated vesicles are required for receptor-mediated endocytosis.

The role of the 100-kDa polypeptide components of clathrin-coated vesicles in endocytosis was investigated by microinjection of specific monoclonal antibodies. Receptor-mediated uptake of transferrin and liposomes was quantitatively inhibited. These results show that the 100-kDa polypeptides are dir...

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Autors principals: Chin, D J, Straubinger, R M, Acton, S, Näthke, I, Brodsky, F M
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC298480/
https://ncbi.nlm.nih.gov/pubmed/2574457
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