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Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor.

Binding of U2 small nuclear ribonucleoprotein (snRNP) to the pre-mRNA branch site is an early step in spliceosome assembly and appears to commit a pre-mRNA to the splicing pathway. We have shown previously that this ATP-dependent binding requires a non-rnRNP factor, U2 snRNP auxiliary factor (U2AF),...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Zamore, P D, Green, M R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2531895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.23.9243
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