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TP53 and MTOR crosstalk to regulate cellular senescence

The full spectrum of activities of the tumor suppressor p53 (TP53) has not been completely elucidated yet. Recently, it was demonstrated that TP53 communicates with the metabolic regulator mechanistic target of rapamycin (MTOR) to determine whether stressed cells undergo cell death, reversible quies...

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Detalhes bibliográficos
Main Authors: Galluzzi, Lorenzo, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984599/
https://ncbi.nlm.nih.gov/pubmed/20876940
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