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Bovine herpesvirus 4 based vector as a potential oncolytic-virus for treatment of glioma

The application of gene therapy for malignant gliomas is still under study and the use of specific vectors represents an important contribution. Here, we investigated bovine herpesvirus 4 (BoHV-4), which is non-pathogenic if injected into the rodent brain. We show that the vector can infect mouse, r...

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Autors principals: Redaelli, Marco, Mucignat-Caretta, Carla, Cavaggioni, Andrea, Caretta, Antonio, D'Avella, Domenico, Denaro, Luca, Cavirani, Sandro, Donofrio, Gaetano
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984596/
https://ncbi.nlm.nih.gov/pubmed/21047419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-298
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