Effects of 2-Bromoethanamine on TonEBP Expression and Its Possible Role in Induction of Renal Papillary Necrosis in Mice

Chronic analgesic abuse has been shown to induce severe renal injury characterized by renal papillary necrosis (RPN), an injury detectable at late stage. While direct toxicity of the drug may exist, the molecular mechanisms underlying analgesics induction of RPN remain unknown. A major limitation to...

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Hlavní autoři: Andres-Hernando, Ana, Lanaspa, Miguel A., Li, Nanxing, Cicerchi, Christina, Roncal-Jimenez, Carlos, Cantor, Glenn H., Sorribas, Victor, Rivard, Christopher J., Berl, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Molecular Toxicology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984534/
https://ncbi.nlm.nih.gov/pubmed/20823374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq261
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