Effects of 2-Bromoethanamine on TonEBP Expression and Its Possible Role in Induction of Renal Papillary Necrosis in Mice

Chronic analgesic abuse has been shown to induce severe renal injury characterized by renal papillary necrosis (RPN), an injury detectable at late stage. While direct toxicity of the drug may exist, the molecular mechanisms underlying analgesics induction of RPN remain unknown. A major limitation to...

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Main Authors: Andres-Hernando, Ana, Lanaspa, Miguel A., Li, Nanxing, Cicerchi, Christina, Roncal-Jimenez, Carlos, Cantor, Glenn H., Sorribas, Victor, Rivard, Christopher J., Berl, Tomas
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
主題:
Molecular Toxicology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984534/
https://ncbi.nlm.nih.gov/pubmed/20823374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq261
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