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Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier

BACKGROUND: The blood-brain barrier (BBB) plays the crucial role of limiting exposure of the central nervous system (CNS) to damaging molecules and cells. Dysfunction of the BBB is critical in a broad range of CNS disorders including neurodegeneration, inflammatory or traumatic injury to the CNS, an...

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Autors principals: Beggs, Simon, Liu, Xue Jun, Kwan, Chun, Salter, Michael W
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984489/
https://ncbi.nlm.nih.gov/pubmed/21044346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-74
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