Integrated Proteomics and Genomics Analysis Reveals a Novel Mesenchymal to Epithelial Reverting Transition in Leiomyosarcoma through Regulation of Slug

Leiomyosarcoma is one of the most common mesenchymal tumors. Proteomics profiling analysis by reverse-phase protein lysate array surprisingly revealed that expression of the epithelial marker E-cadherin (encoded by CDH1) was significantly elevated in a subset of leiomyosarcomas. In contrast, E-cadhe...

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Detalhes bibliográficos
Main Authors: Yang, Jilong, Eddy, James A., Pan, Yuan, Hategan, Andrea, Tabus, Ioan, Wang, Yingmei, Cogdell, David, Price, Nathan D., Pollock, Raphael E., Lazar, Alexander J. F., Hunt, Kelly K., Trent, Jonathan C., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984227/
https://ncbi.nlm.nih.gov/pubmed/20651304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.000240
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