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RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila

Activation of innate antiviral responses in multicellular organisms relies on the recognition of structural differences between viral and cellular RNAs. Double-stranded (ds)RNA, produced during viral replication, is a well-known activator of antiviral defenses and triggers interferon production in v...

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Detalhes bibliográficos
Main Authors: Mueller, Stefanie, Gausson, Valérie, Vodovar, Nicolas, Deddouche, Safia, Troxler, Laurent, Perot, Jonathan, Pfeffer, Sébastien, Hoffmann, Jules A., Saleh, Maria-Carla, Imler, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984213/
https://ncbi.nlm.nih.gov/pubmed/20978209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014378107
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