Hypoxia abrogates antichlamydial properties of IFN-γ in human fallopian tube cells in vitro and ex vivo

IFN-γ has an important role in the adaptive immune response against intracellular pathogens. In urogenital tract (UGT) infections with the obligate intracellular pathogen Chlamydia trachomatis, IFN-γ–mediated control of chlamydial growth implies the JAK-STAT signaling cascades and subsequent inducti...

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Autors principals: Roth, Anna, König, Peter, van Zandbergen, Ger, Klinger, Matthias, Hellwig-Bürgel, Thomas, Däubener, Walter, Bohlmann, Michael K., Rupp, Jan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984208/
https://ncbi.nlm.nih.gov/pubmed/20974954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008178107
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