Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7–induced signaling

Thymic stromal lymphopoietin (TSLP) is a type I cytokine that plays essential roles in allergic/inflammatory skin and airway disorders, in helminth infections, and in regulating intestinal immunity. TSLP signals via IL-7Rα and a specific TSLPR subunit that is highly related to the common cytokine re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rochman, Yrina, Kashyap, Mohit, Robinson, Gertraud W., Sakamoto, Kazuhito, Gomez-Rodriguez, Julio, Wagner, Kay-Uwe, Leonard, Warren J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984176/
https://ncbi.nlm.nih.gov/pubmed/20974963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008271107
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