Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis

The neuropeptide vasoactive intestinal peptide (VIP) has been shown to inhibit macrophage proinflammatory actions, promote a positive Th2/Th1 balance, and stimulate regulatory T-cell production. The fact that this peptide is highly efficacious in animal models of inflammatory diseases such as collag...

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Detalhes bibliográficos
Main Authors: Abad, Catalina, Tan, Yossan-Var, Lopez, Robert, Nobuta, Hiroko, Dong, Hongmei, Phan, Phu, Feng, Ji-Ming, Campagnoni, Anthony T., Waschek, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984164/
https://ncbi.nlm.nih.gov/pubmed/20978211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007622107
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