Alloreactivity studied with mutants of HLA-A2.

Based on the crystal structure of HLA-A2.1 and the recognition of a panel of mutant HLA-A2.1 molecules by a large number of alloreactive cytotoxic T lymphocyte clones, a model to explain alloreactivity is described. In this model recognition of an allogeneic major histocompatibility complex molecule...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Santos-Aguado, J, Crimmins, M A, Mentzer, S J, Burakoff, S J, Strominger, J L
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1989
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8936
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