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Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells.

The effects of several hematopoietic growth factors on primitive murine bone marrow progenitor cells [colony-forming unit(s)-spleen (CFU-S)] have been investigated during culture for 2-6 days. Interleukin 3 (IL-3) was required for CFU-S survival in culture, and the combination of IL-3 and interleuki...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bodine, D M, Karlsson, S, Nienhuis, A W
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813429/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8897
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