Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid.

Myristoyl-CoA:protein N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the cotranslational linkage of myristate to the N-terminal glycine residues of several cellular, viral, and oncoproteins. We have recently synthesized a series of sulfur- and oxygen-substituted analogs of myristic acid that ar...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Bryant, M L, Heuckeroth, R O, Kimata, J T, Ratner, L, Gordon, J I
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1989
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813417/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8655
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