Isolation and expression of the Pneumocystis carinii dihydrofolate reductase gene.

Pneumocystis carinii dihydrofolate reductase (DHFR; 5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, EC 1.5.1.3) cDNA sequences have been isolated by their ability to confer trimethoprim resistance to Escherichia coli. Consistent with the recent conclusion that P. carinii is a member of the Fungi, se...

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Bibliographic Details
Main Authors: Edman, J C, Edman, U, Cao, M, Lundgren, B, Kovacs, J A, Santi, D V
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC298340/
https://ncbi.nlm.nih.gov/pubmed/2682653
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