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Mitotic spindle disassembly occurs via distinct subprocesses driven by the anaphase-promoting complex, Aurora B kinase, and kinesin-8

The mitotic spindle is a complex and dynamic structure. Although much has been learned about how spindles assemble and mediate chromosome segregation, how spindles rapidly and irreversibly disassemble during telophase is less clear. We used synthetic lethal screens in budding yeast to identify mutan...

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Bibliographic Details
Main Authors: Woodruff, Jeffrey B., Drubin, David G., Barnes, Georjana
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2983061/
https://ncbi.nlm.nih.gov/pubmed/21079246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006028
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