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Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells.

Prostaglandins (PGs) A1 and J2 were found to potently suppress the proliferation of human K562 erythroleukemia cells and to induce the synthesis of a 74-kDa protein (p74) that was identified as a heat shock protein related to the major 70-kDa heat shock protein group. p74 synthesis was stimulated at...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Santoro, M G, Garaci, E, Amici, C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298291/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2813398/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8407
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