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Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics and Effect on the Insulin-like Growth Factor Axis

Resveratrol, a naturally occurring polyphenol, has cancer chemopreventive properties in preclinical models. It has been shown to downregulate levels of insulin-like growth factor-1 (IGF-1) in rodents. The purpose of the study was to assess its safety, pharmacokinetics and effects on circulating leve...

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書誌詳細
主要な著者: Brown, Victoria A, Patel, Ketan R, Viskaduraki, Maria, Crowell, James A, Perloff, Marjorie, Booth, Tristan D, Vasilinin, Grygoriy, Sen, Ananda, Schinas, Anna Maria, Piccirilli, Gianfranca, Brown, Karen, Steward, William P, Gescher, Andreas J, Brenner, Dean E
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982884/
https://ncbi.nlm.nih.gov/pubmed/20935227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2364
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