Targeting human clonogenic acute myelogenous leukemia cells via folate conjugated liposomes combined with receptor modulation by all-trans retinoic acid

Our previous data demonstrated that folate receptor β (FR-β) targeted liposomal doxorubicin (FT-L-DOX) showed enhanced cytotoxicity relative to non-targeted liposomal doxorubicin (CON-L-DOX), and the effect was enhanced by selective FR-β upregulation by all-trans retinoic acid (ATRA) in AML blast ce...

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Hlavní autoři: Li, Hong, Lu, Yanhui, Piao, Longzhu, Wu, Jun, Liu, Shujun, Marcucci, Guido, Ratnam, Manohar, Lee, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982872/
https://ncbi.nlm.nih.gov/pubmed/20883757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.09.019
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