The Effect of Gentamicin-Induced Readthrough on a Novel Premature Termination Codon of CD18 Leukocyte Adhesion Deficiency Patients

BACKGROUND: Leukocyte adhesion deficiency 1 (LAD1) is an inherited disorder of neutrophil function. Nonsense mutations in the affected CD18 (ITB2) gene have rarely been described. In other genes containing such mutations, treatments with aminoglycoside types of antibiotics (e.g., gentamicin) were re...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Simon, Amos J., Lev, Atar, Wolach, Baruch, Gavrieli, Ronit, Amariglio, Ninette, Rosenthal, Ester, Gazit, Ephraim, Eyal, Eran, Rechavi, Gideon, Somech, Raz
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982813/
https://ncbi.nlm.nih.gov/pubmed/21103413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013659
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares